ماهر الصغير

رئيس ومدير قسم المختبرات وعلم الأمراض

المؤهلات العلمية

1983: بكالوريس الطب والجراحة من الجامعة الأردنية.
الإقامة في مستشفى نيوانجلند ديكونس، جامعة هارفرد، بوسطن، الولايات المتحدة الأمريكية.
الزمالة في مستشفى وجامعة جونز هوبكنز، بالتمور، الولايات المتحدة الأمريكية.

شهادات البورد

البورد الأمريكي في علم الأمراض.
البورد الأمريكي في المختبرات الطبية.
البورد الأمريكي في علم أمراض الخلايا.

الإصدارات

Aladily TN, Mansour A, Alsughayer A, Sughayer M, Medeiros LJ. The utility of CD83, fascin and CD23 in the differential diagnosis of primary mediastinal large B-cell lymphoma versus classic Hodgkin lymphoma. Ann Diagn Pathol. 2019 Apr 23;40:72-76. 10.1016/j.anndiagpath.2019.04.009. [Epub ahead of print]
Abualhaj NZ, Dardas Z, Azab B, Ali D, Sughayer MA, Aladily TN, Ahram M. The frequency of NOTCH1 variants in T-acute lymphoblastic leukemia/lymphoma and chronic lymphocytic leukemia/small lymphocytic lymphoma among Jordanian patients. Ann Diagn Pathol. 2019 Apr;39:53-58. doi: 10.1016/j.anndiagpath.2019.01.004. Epub 2019 Jan 24.
Safadi RA, Abdullah NI, Alaaraj RF, Bader DH, Divakar DD, Hamasha AA, Sughayer MA. Clinical and histopathologic prognostic implications of the expression of cytokeratins 8, 10, 13, 14, 16, 18 and 19 in oral and oropharyngeal squamous cell carcinoma. Arch Oral Biol. 2019 Mar;99:1-8. doi: 10.1016/j.archoralbio.2018.12.007. Epub 2018 Dec 16.
Abdullah N, Hajeer M, Abudalu L, Sughayer M. "Correlation study of thyroid nodule cytopathology and histopathology at two institutions in Jordan."Cytojournal.15;15:24.doi:10.4103/cytojournal.cytojournal_53_17. eCollection 2018.PMID: 30410561 2018Oct.
Abu-Duhier FM, Javid J, Sughayer MA, Mir R, Albalawi T, Alauddin MS. "Clinical Significance of Circulatory miRNA-21 as an Efficient Non-Invasive Biomarker for the Screening of Lung Cancer Patients." Asian Pac J Cancer Prev. 26;19(9):2607-2611. PMID: 30256067 2018 Sep.
Sughayer M, Alaaraj R, Alsughayer A. "Applying new Magee equations for predicting the Oncotype Dx recurrence score." Breast Cancer. 2018 Sep;25(5):597-604. doi: 10.1007/s12282-018-0860-x. Epub 2018 Apr 24. PMID:29691722, 2018 Sep.
Sughayer MA, Alnaimy F, Alsughayer AM, Qamhia N. "Comparison of 22C3 PharmDx and SP263 Assays to Test PD-L1 Expression in NSCLC." Appl Immunohistochem Mol Morphol.doi: 1097/PAI.0000000000000671. [Epub ahead of print] PMID: 30024424 2018 Jul 17.
Sughayer MA, Abdullah N , The Bethesda System for Reporting Thyroid Cytopathology: A Meta-Analysis. Acta Cytol. 2017 Feb 7. doi: 10.1159/000455116
Alaaraj R, Lataifeh I, Elsaadi J, Salameh M, Sughayer M. Primary low-grade endometrioid stromal sarcoma of the ovary with multiple omental metastases. Gulf Medical Journal. 2016;5(1):69–73
Souan L, Tout F, Siag M, Sughayer MA. "Seroprevalence rates of transfusion-transmitted infections among blood donors in Jordan". J Infect Dev Ctries. 2016 Apr 28;10(4):377-83. doi: 10.3855/jidc.8160.
Safadi RA, Bader DH, Abdullah NI, Sughayer MA. Immunohistochemical expression of keratins 6, 7, 8, 14, 16, 18, 19 and MNF-116 pancytokeratin in primary and metastatic melanoma of the head and neck. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 12/2015; DOI:10.1016/j.oooo.2015.11.016
Sughayer MA, Souan L. Establishing an Iso-Compliant Modern Cancer-Biobank in a Developing Country: A Model for International Cooperation Adv Exp Med Biol. 2015;864:141-55. doi: 10.1007/978-3-319-20579-3_11.
Al-Kzayer LF, Sakashita K, Al-Jadiry MF, Al-Hadad SA, Ghali HH, Uyen le TN, Liu T, Matsuda K, Abdulkadhim JM, Al-Shujairi TA, Matti ZI, Sughayer MA, Rihani R, Madanat FF, Inoshita T, Kamata M, Koike K. Analysis of KRAS and NRAS Gene Mutations in Arab Asian Children With Acute Leukemia: High Frequency of RAS Mutations in Acute Lymphoblastic Leukemia. Pediatr Blood Cancer. 2015 Dec;62(12):2157-61. doi:10.1002/pbc.25683. Epub 2015 Jul 29.
Hussein AA, Hamadah T, Qandeel M, Sughayer M, Amarin R, Mansour A, Chiang SC, Al-Zaben A, Meeths M, Bryceson YT. Hematopoietic Stem Cell Transplantation of an Adolescent with Neurological Manifestations of Homozygous Missense PRF1 Mutation. Pediatr Blood Cancer. 2014 Aug 11.
Al-Kzayer LF, Sakashita K, Al-Jadiry MF, Al-Hadad SA, Uyen LT, Liu T, Matsuda K, Abdulkadhim JM, Al-Shujairi TA, Matti ZI, Hasan JG, Al-Abdullah HM, Inoshita T, Kamata M, Sughayer MA, Madanat FF, Koike K. Frequent Coexistence of RAS Mutations in RUNX1-Mutated Acute Myeloid Leukemia in Arab Asian Children. 2014 Wiley Periodicals, Inc. 2014 Jul 25. doi: 10.1002/pbc.25151.
Barr, M., Souan, L., MacGabhann, P., Müller, J., Al Ashhab, M., Jasser, M. Hamza, K., Sughayer, M. A. (2014). The Establishment of an ISO Compliant Cancer Biobank for Jordan and its Neighboring Countries Through Knowledge Transfer and Training. Biopreservation and Biobanking, 12(1), 3-12.
Maher A. Sughayer, Hussam A. Haddad, Rana M. Al-Yousef, Hanood Abu-Rass. Epstein-Barr virus and Hodgkin lymphoma in Jordan; Hematology/ Oncology and Stem Cell Therapy, 2014 Jan 25. pii: S1658-3876(14)00003-X. doi: 10.1016/j.hemonc.2013.12.002.
M Al-Masri, G Darwazeh, M El-Ghanem, B Hamdan, M Sughayer; Assessment of an existing and modified model for predicting non sentinel lymph node metastasis in breast cancer patients with positive sentinel node biopsy. Gulf journal of oncology, 2013; 1(13):15-22.
Rita T. Lawlor, Patrick M. Sluss, Rupert Langer, Maher A. Sughayer, Michael A. Igbe, Khalid Siddiqui, Pasquale De Blasio, Bonginkosi Duma, Maimuna Mendy, Christian Chabannon, Muntaser Ibrahim. European, Middle Eastern, and African Society for Biopreservation and Biobanking (ESBB). 2012 Conference Session on Biobanking in Emerging Countries, Biopreservation and Biobanking, 2013; 11(3):176.
Maher A. Sughayer. Epstein–Barr virus and Hodgkin’s lymphoma in Cairo, Egypt; Journal of Hematopathology. 2013; 6(1).
Laila Moharram, Nazmi Kamal, Sana Al Sukhun, Maher A Sughayer. Erythropoietin-induced acute erythroid leukemia-like picture: A potential pitfall. ; Hematol Oncol Stem Cell Ther. 2014 Mar;7(1):50-2. doi: 10.1016/j.hemonc.2013.09.004. Epub 2013 Nov 14.
Bilal Baker, Basem Morcos, Faiez Daoud, Maher Sughayer, Hisham Shabani, Habeeb Salameh, Mahmoud Almasri. Histo-biological comparative analysis of bilateral breast cancer. Medical Oncology, 2013; 30(4):711.
Al-Masri M, Darwazeh G, El-Ghanem M, Hamdan B, Sughayer M. Assessment of an existing and modified model for predicting non sentinel lymph node metastasis in breast cancer patients with positive sentinel node biopsy, Gulf J Oncolog. 2013 Jan;1(13):15-22.
Barakat FH, Sulaiman I, Sughayer MA. Reliability of frozen section in breast sentinel lymph node examination. Breast Cancer. 2012 Nov 29. [Epub ahead of print] PMID: 23192628.
Elbjeirami WM, Sughayer MA. KRAS mutations and subtyping in colorectal cancer in Jordanian patients. Oncol Lett. 2012 Oct;4(4):705-710. Epub 2012 Jul 4. PMID: 23205087.
Hashem SA, Salem A, Al-Rashdan A, Ezam N, Nour A, Alsharbaji A, Rejeeth C, Mohamad I, Sughayer M, Elyan M, Al-Hussaini M, Addasi A, Almousa A. Radiotherapy with concurrent or sequential temozolomide in elderly patients with glioblastoma multiforme. J Med Imaging Radiat Oncol. 2012 Apr;56(2):204-10. doi: 10.1111/j.1754-9485.2011.02325.x. PMID: 22498195.
Slem A, Abu-Hijlih R, Abdelrahman F, Turfa R, Amarin R, Farah N, Sughayer M, Almousa A, Khader J. Eight primary malignancies: case report and review of literature. Hematol Oncol Stem Cell Ther. 2011;4(4):185-7. doi: 10.5144/1658-3876.2011.185.
Al-Masri M, Darwazeh G, Sawalhi S, Mughrabi A, Sughayer M, Al-Shatti M. Phyllodes Tumor of the Breast: Role of CD10 in Predicting Metastasis. Ann Surg Oncol 2011 Oct 18 [Epub ahead of print] PMID: 22006372.
R Al-Zagha, M Sughayer, A Sandouka, F Hamadeh. Epidemiologic Evaluation of Cervical Smear Findings in West Bank/Palestine: A Retrospective Study; An-Najah University Journal for research 2011 (1), 26-30
Tihan T, Ersen A, Qaddoumi I, Sughayer MA, Tolunay S, Al-Hussaini M, Phillips J, Gupta N, Goldhoff P, Baneerjee A., Pathologic Characteristics of Pediatric Intracranial Pilocytic Astrocytomas and Their Impact on Outcome in 3 Countries: A Multi-institutional Study. Am J Surg Pathol. 2011 Oct 10 [Epub ahead of print] PMID: 21989351.
Salem A, Hashem SA, Al-Rashdan A, Ezam N, Nour A, Alsharbaji A, Sughayer M, Mohamad I, Elyan M, Addas A, Al-Hussaini M, Almousa A., The challenges of managing glioblastoma multiforme in developing countries: a trade-off between cost and quality of care. Hematol Oncol Stem Cell Ther. 2011 Third Quarter;4(3):116-120 PMID: 21982884.
Salem A, Abu-Hijlih R, Abdelrahman F, Turfa R, Amarin R, Farah N, Sughayer M, Almousa A, Khader J., Multiple Primary Malignancies: Analysis of 23 Patients with at Least Three Tumors. J Gastrointest Cancer. 2011 Jun 25 [Epub ahead of print] PMID: 21706155.
Ismail SI, Mahmoud IS, Salman MA, Sughayer MA, Mahafzah AM., Frequent detection of Human Herpes Virus-8 in bone marrow of Jordanian patients of multiple myeloma, Cancer Epidemiol. 2010 Dec 1 [Epub ahead of print].
Lataifeh I, Abdel-Hadi M, Morcos B, Sughayer M, Barahmeh S. Papillary thyroid carcinoma arising from mature cystic teratoma of the ovary, J Obstet Gynaecol. 2010; 30(8):884-6.
Janem W, Sultan I, Ajlouni F, Deebajah R, Haddad H, Sughayer MA, Goussous RY.. Malignant insulinoma in a child. Pediatr Blood Cancer, 2010 Dec 15; 55(7):1423-6.
Barakat FH, Haddad HA, Maralka II, Al-Orjani MS, Al-Masri MM, Sughayer MA, Characteristics of gastrointestinal stromal tumors in a Middle Eastern population, Saudi Med J. 2010 Jul;31(7):797-802.
Al Nassan A, Sughayer M, Matalka I, Ghandour K, Masarweh M, Zimmermann A, Sultan I. INI1 (BAF 47) Immunohistochemistry is an Essential Diagnostic Tool for Children With Hepatic Tumors and Low Alpha Fetoprotein, J Pediatr Hematol Oncol. 2010 Mar; 32(2):e79-81.
Ismail SI, Mahmoud IS, Msallam MM, Sughayer MA. Hotspot mutations of PIK3CA and AKT1 genes are absent in multiple myeloma. Leuk Res. 2010 Jun; 34(6):824-6. Epub 2009 Dec 22.
Sughayer M, Abdelhadi M, Abdeen G, Otay L, Dayeh T. Human papillomavirus genotypes in invasive cervical cancer in Jordan, Int J Gynaecol Obstet. 2010 Jan;108(1):74-5.
Sughayer M, Zakarneh L, Abu Shakra R. Collision Metastasis of Breast and Ovarian Adenocarcinoma in Axillary Lymph Nodes, A Case Report and Review of the Literature. Pathol Oncol Res, 2009 Sep; 15(3):423-7. Epub. 2008, Dec. 9.
Mahmoud IS, Sughayer MA, Mohammad HA, Awidi AS, EL-Khateeb MS, Ismail SI. The transforming mutation E17K/AKT1 is not a major event in B-cell-derived lymphoid leukaemias. Br J Cancer. 2008 Aug 5; 99(3):488-90.
Haddad H, Joudeh A, El-Taani H, Mansour A, Morcos B, Fayoumi S, Sughayer M. Thymoma and Thymic Carcinoma Arising in a Thymolipoma: Report of a Unique Case. Int J Surg Pathol 2009 Feb, 17 (1): 55-9. Epub 2008 May 14.
Ismail. S, Sughayer.M, Al-Quadan.T, Qaqish.B, Tarawneh. M. Frequency of T (14; 18) in follicular lymphoma Patients: geographical or technical variation. Int J Lab Hematol. 2009 Oct; 31(5):535-43. Epub 2008 May 21.
Qaddoumi I, Ceppa EP, Mansour A, Sughayer M, Tihan T. Desmoplastic noninfantile ganglioglioma: report of a case. Pediatr Dev Pathol. 2006 Nov-Dec; 9(6):462-7.
Sughayer M, Al-Khawaja M, Massarweh S, Al-Masri M. Prevalence of Hormone Receptors and HER2/neu in Breast Cancer Cases in Jordan. Pathol Oncol Res. 2006; 12 (2):83-6.
Mansour A, Qandeel M, Sughayer M, Kamona A, Swaidan M, Khawaja M. Solid (stromal predominance) hepatic mesenchymal hamartoma. Pediatr Radiol. 2005 Mar; 35(3):349-50.
Ayesh B, Matouk I, Ohana P, Sughayer M, Birman T, Ayesh S, Schneider T, de Groot N, Hochberg A. Inhibition of tumor growth by DT-A expressed under the control of IGF2 P3 and P4 promoter sequences. Mol Ther. 2003 Apr; 7(4):535-41.
Darwish H, Trejo IE, Shapira I, Oweineh S, Sughayer M, Baron L, Aljadeff E, Silbermann M, Swaidan W, Zilberg D, Halpern Z, Hibshoosh H, Arber N. Fighting colorectal cancer: molecular epidemiology differences among Ashkenazi and Sephardic Jews and Palestinians. Ann Oncol. 2002 Sep; 13(9):1497-501.
Shochina M, Fellig Y, Sughayer M, Pizov G, Vitner K, Podeh D, Hochberg A, Ariel I. Nitric oxide synthase immunoreactivity in human bladder carcinoma. Mol Pathol. 2001 Aug; 54(4):248-52.
Ariel I, Sughayer M, Fellig Y, Pizov G, Ayesh S, Podeh D, Libdeh BA, Levy C, Birman T, Tykocinski ML, de Groot N, Hochberg A. The imprinted H19 gene is a marker of early recurrence in human bladder carcinoma. Mol Pathol. 2000 Dec; 53(6):320-3.
Abdul-Ghani R, Ohana P, Matouk I, Ayesh S, Ayesh B, Laster M, Bibi O, Giladi H, Molnar-Kimber K, Sughayer M, de Groot N, Hochberg A. Use of transcriptional regulatory sequences of telomerase (hTER and hTERT) for selective killing of cancer cells. Mol Ther. 2000 Dec; 2(6):539-44.
Khatib H, Sughayer M, Ayesh S. The distribution of the vWF alleles and genotypes in the Palestinian population. J Forensic Sci. 1997; 42 (3): 504-505.
Sughayer M, Ali S, Erozan Y, Dunsmore N, Hall S. Pulmonary malacoplakia associated with Rhodococcus equi infection in an AIDS patient. Acta cytol. 1997; 41(2):507-512.
Sughayer M. Transfusion Services in the occupied Palestinian Territories. Transfusion today. 1994; 19: 8-9.
Sughayer M. Fine needle Aspiration, the experience of Makassed Islamic Hospital, Al-Quds Medical Journal. 1994; 2: 11-17.
Mayan S, Shinar E, Aefani M, Sughayer M, El-Khoudary R, Rahav G, Manny N, HIV\AIDS among Palestinian Arabs. Isr J Med-Sci. 1993; 29 (10 Suppl): 7-10
Sherman M, Weinstein M, Sughayer M, Cappellari J, Orr J , Erozan Y, Schiffman M, Kurman R. The Bethesda System; Impact on Reporting Cervicovaginal Specimens and Reproducibility of Criteria for Assessing Endocervical Sampling. Acta Cytologica. 1993; 37(1): 55-60
Sughayer M, Arkin CF. Unusual band on hemoglobin electrophoresis produced by a monoclonal immunoglobulin in serum. Clin Chem.1989; 35: 1794.
Sughayer M, Arkin CF. Monitoring coagulation during and after cardiopulmonary bypass surgery. Check Sample, American Society of Clinical Pathology, Chicago, IL, Thrombosis and Hemostasis. 12(4), 1990.
Sughayer M, DeGirolami PC, Khettry U, Korzeniowski D, Grumney A, Pasarell L, McGinnis MR. Human infection caused by Exophiala pisciphila: case report and review. Rev Infect Dis. 1991 May-Jun; 13(3):379-82.
Nichols L, Sughayer M, DeGirolami PC, Balogh K, Pleskow D, Eichelberger K, Santos M. Evaluation of diagnostic methods for Helicobacter pylori gastritis. Am J Clin Pathol. 1991 Jun; 95(6):769-773.
Killeen KP, Libertino JA, Sughayer M, Lee AK, Watkins E Jr. Pathologic review of consecutive radical prostatectomy specimens. Nerve sparing versus non-nerve sparing. J. Urology. 1991 Sep; 38(3):212-5.
Henin D, Smith TW, De Girolami U, Sughayer M, Hauw JJ. Neuropathology of the spinal cord in the Acquired Immunodeficiency Syndrome: A study of 138 cases and review of the literature. Hum Pathol. 1992 Oct; 23(10):1106-14.
Sughayer MA, Souan L. Establishing an Iso-Compliant Modern Cancer-Biobank in a Developing Country: A Model for International Cooperation. In F. Karimi-Busheri (ed.), Biobanking in the 21st Century, Advances in Experimental Medicine and Biology 864, DOI 10.1007/978-3-319-20579-3_11, New York, Springer International Publishing, 2015.
Souan L, Sughayer MA. Innovative Approaches in Quality Management in Clinical Laboratories, In Ognyan Ivanov (Ed.), Applications and Experiences of Quality Control ISBN: 978-953-307-236-4, InTech. 2011.

معلومات الاتصال

البريد الإلكتروني:msughayer@khcc.jo
رقم الهاتف: 0096265300460 -1551